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Solid dosage forms

  • Pan coater GS FILM RA/F
  • Pan coater Logica Progetti Tech 10
  • Alternate tableting machine Korsch EK0
  • Rotary tablet press Ronchi AM-8S e relativo sistema di acquisizione delle forze FDW Analyser
  • Rotary tablet press Ronchi FA e relativo sistema di acquisizione delle forze
  • Three-dimensional printer Cronoplast (for 3D printing of thermoplastic materials)
  • Extractor (continuous mode) Soxlet
  • Extruder (Extrusiograph 19/25 D, Brabender) equipped with cutter for spherical extrudates and data acquisition/analysis softwarei
  • Single-screw extruder Brabender PL2000
  • Extruder/sheronizer Nica System
  • Extruder /bench-top twin-screw capillary rheometer Thermo Fisher HAAKE MiniLab II
  • One-step high-shear granulator Rotolab Zanchetta
  • Fluid bed apparatus Uniglatt
  • Bench-top fluid bed apparatus Mini-Glatt
  • Stator homogenizer Ultraturrax
  • Injection-molding press Baby Plast 6/10P
  • Fluid bed rotogranulator Glatt GPGC 1.1
  • Sealing machine Mini Pack
  • Bench-top single-arm FDM (Fused Deposition Modeling) 3D printer, Makerbot Replicator 2
  • Bench-top dual-arm FDM 3D printer, Kloner3D 240 Twin
  • 3D Discovery Evolution Bioprinter, Regen-Hu R-GEN 100 equipped with different printer heads

Freeze-dried products

  • Freeze-dryer alpha 1-4 LSC
  • Bench-top freeze-dryer (6 kg water) Martin Christ


  • Ball mill Morandi
  • Hammer mill Retsch ZM200
  • Spray-dryer 4M8 PROCEPT

Topical dosage forms

  • Stator homogenizer
  • Mathis Labcoater type LTE-S(M)
  • hot-melt ram-extrusion 3D printer
  • Mini-extruder for liposome formulations (Avanti polar lipids, USA)
  • Brookfield Viscosimeter

Parenteral dosage forms

  • Autoclave (Tuttnauer 2540 mL)
  • Shaking incubator (CERTOMAT IS, Sartorius)


In vitro skin and mucosal permeation

  • Franz diffusion cells for in vitro evaluation of skin and transmucosal permeability of active ingredients

Solid state properties

  • Differential scanning calorimeter MODULATO Mettler
  • Thermobalance TA Instruments 2050

Mechanical properties

  • Instron dynamometer equipped for measuring the mechanical properties of plastic materials, adhesives, and material with mucoadhesive properties
  • ACQUATI AGMC1 dynamometer equipped for the measurement of the mechanical properties of plastic materials, siringability and injectability tests
  • Plastometer

Granulometry and Particle size distribution

  • Coulter Beckmann BET for surface area measurements
  • Laser Diffraction Particle Size Analyzers For Both Wet And Dry Dispersion (Mastersizer 3000)
  • Optical microscope Zeiss mod. Axiolab equipped for particle size analysis accordingto British Standard 3406
  • Sieve shaker Endecotts mod. Octagon 200 for sieve analysis
  • Dynamic light scattering, Malvern Zetasizer Nano SZ
  • Nano tracking analysis, NanoSight NS300

Spectroscopy analysis

  • High performance liquid chromatographs (HPLC) equipped with autosampler and the following detection systems: UV-DAD, and fluorimeter
  • GPC equipped with RID detector
  • UV-Vis spectrophotometers

Testing of dosage forms

  • Dissolution apparatus Ph. Eur.
  • Disaggregation apparatus Ph. Eur.
  • Friability Test Instrument Erweka mod. TA3R
  • Creep instrument (8 bank oven shear HT-8, Cheminstruments)
  • Karl Fischer titrator (Mettler Toledo V20)
  • Oscillating water bath (Julabo)
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