Sezione Chimica Farmaceutica "P. Pratesi"
The identification of new chemical entities with targeted biological activity is an essential requirement for the development of new, more active, and safer drugs, a goal that implies a multidisciplinary and synergistic scientific approach.
Professors and researchers of the Medicinal Chemistry Section of DISFARM possess specific scientific skills in synthetic, analytical, and computational chemistry.
The investigated research fields range from the design, synthesis, structural and physico-chemical characterization of new compounds active on different biological targets to molecular modeling investigations, from the assessment of biological activity to the study of chemical and metabolic stability in vitro and in vivo pharmacokinetic and metabolic profile of drugs, from the characterization and quantitative determination of diagnostic and prognostic biomarkers in biological fluids to chemical-toxicological analyses. The themes developed in these scientific areas are detailed in the profiles of individual research units.